| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Bccel_0777 | Bccel_1565 | Bccel_0777 | Bccel_1565 | PFAM: Inosine monophosphate cyclohydrolase-like protein; KEGG: hypothetical protein. | KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein. | 0.826 |
| Bccel_0777 | Bccel_3555 | Bccel_0777 | Bccel_3555 | PFAM: Inosine monophosphate cyclohydrolase-like protein; KEGG: hypothetical protein. | PFAM: AICARFT/IMPCHase bienzyme; KEGG: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme. | 0.962 |
| Bccel_0777 | Bccel_3705 | Bccel_0777 | Bccel_3705 | PFAM: Inosine monophosphate cyclohydrolase-like protein; KEGG: hypothetical protein. | TIGRFAM: phosphoribosylformylglycinamidine synthase; KEGG: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein, AIR synthase related protein. | 0.895 |
| Bccel_0777 | glyA | Bccel_0777 | Bccel_1518 | PFAM: Inosine monophosphate cyclohydrolase-like protein; KEGG: hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.563 |
| Bccel_0777 | purD | Bccel_0777 | Bccel_2241 | PFAM: Inosine monophosphate cyclohydrolase-like protein; KEGG: hypothetical protein. | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain-containing protein, Phosphoribosylglycinamide synthetase, N-domain-containing protein, Phosphoribosylglycinamide synthetase, C-domain-containing protein; TIGRFAM: phosphoribosylamine/glycine ligase; HAMAP : Phosphoribosylamine--glycine ligase; KEGG: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.704 |
| Bccel_0777 | purN | Bccel_0777 | Bccel_2243 | PFAM: Inosine monophosphate cyclohydrolase-like protein; KEGG: hypothetical protein. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.968 |
| Bccel_1321 | Bccel_1565 | Bccel_1321 | Bccel_1565 | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein. | 0.906 |
| Bccel_1321 | Bccel_3555 | Bccel_1321 | Bccel_3555 | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: AICARFT/IMPCHase bienzyme; KEGG: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme. | 0.992 |
| Bccel_1321 | Bccel_3705 | Bccel_1321 | Bccel_3705 | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: phosphoribosylformylglycinamidine synthase; KEGG: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein, AIR synthase related protein. | 0.995 |
| Bccel_1321 | Bccel_4171 | Bccel_1321 | Bccel_4171 | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; KEGG: glutamine phosphoribosylpyrophosphate amidotransferase; PFAM: glutamine amidotransferase class-II, phosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.976 |
| Bccel_1321 | glyA | Bccel_1321 | Bccel_1518 | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.898 |
| Bccel_1321 | purC | Bccel_1321 | Bccel_4033 | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; HAMAP : Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.999 |
| Bccel_1321 | purD | Bccel_1321 | Bccel_2241 | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain-containing protein, Phosphoribosylglycinamide synthetase, N-domain-containing protein, Phosphoribosylglycinamide synthetase, C-domain-containing protein; TIGRFAM: phosphoribosylamine/glycine ligase; HAMAP : Phosphoribosylamine--glycine ligase; KEGG: phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.995 |
| Bccel_1321 | purF | Bccel_1321 | Bccel_2245 | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.980 |
| Bccel_1321 | purN | Bccel_1321 | Bccel_2243 | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.984 |
| Bccel_1565 | Bccel_0777 | Bccel_1565 | Bccel_0777 | KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein. | PFAM: Inosine monophosphate cyclohydrolase-like protein; KEGG: hypothetical protein. | 0.826 |
| Bccel_1565 | Bccel_1321 | Bccel_1565 | Bccel_1321 | KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein. | SMART: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; KEGG: adenylosuccinate lyase; PFAM: Lyase 1, N-terminal, Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.906 |
| Bccel_1565 | Bccel_3555 | Bccel_1565 | Bccel_3555 | KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein. | PFAM: AICARFT/IMPCHase bienzyme; KEGG: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme. | 0.991 |
| Bccel_1565 | Bccel_3705 | Bccel_1565 | Bccel_3705 | KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein. | TIGRFAM: phosphoribosylformylglycinamidine synthase; KEGG: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein, AIR synthase related protein. | 0.945 |
| Bccel_1565 | Bccel_4171 | Bccel_1565 | Bccel_4171 | KEGG: IMP dehydrogenase/GMP reductase; PFAM: IMP dehydrogenase/GMP reductase, CBS domain containing protein. | Amidophosphoribosyltransferase; KEGG: glutamine phosphoribosylpyrophosphate amidotransferase; PFAM: glutamine amidotransferase class-II, phosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.902 |