STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKS-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (397 aa)    
Predicted Functional Partners:
Bccel_1504
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.954
Bccel_5564
Methionine synthase; PFAM: homocysteine S-methyltransferase, cobalamin B12-binding domain protein, Methionine synthase B12-binding module cap domain protein, dihydropteroate synthase DHPS; KEGG: homocysteine S-methyltransferase; SMART: Methionine synthase B12-binding module cap domain protein.
  
 
 0.954
Bccel_2345
TIGRFAM: 5,10-methylenetetrahydrofolate reductase; KEGG: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.935
Bccel_1865
dTDP-glucose 4,6-dehydratase; KEGG: NAD dependent epimerase; PFAM: NAD-dependent epimerase/dehydratase.
   
 0.899
Bccel_2088
KEGG: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase.
   
 0.899
Bccel_3162
dTDP-glucose 4,6-dehydratase; KEGG: hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase.
   
 0.899
Bccel_4012
PFAM: NAD-dependent epimerase/dehydratase; KEGG: nucleoside-diphosphate-sugar epimerase.
   
 0.899
Bccel_5291
PFAM: NAD-dependent epimerase/dehydratase; KEGG: CDP-abequose synthase.
   
 0.899
Bccel_5292
Hypothetical protein; KEGG: CDP-abequose synthase.
   
 0.899
Bccel_5293
UDP-glucuronate decarboxylase; KEGG: NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase.
   
 0.899
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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