STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bccel_4367KEGG: molecular chaperone DnaJ; PFAM: heat shock protein DnaJ domain protein, chaperone DnaJ domain protein; SMART: heat shock protein DnaJ domain protein. (312 aa)    
Predicted Functional Partners:
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 0.994
Bccel_4457
PFAM: Heat shock protein 70; KEGG: molecular chaperone.
 0.993
Bccel_5599
PFAM: Heat shock protein 70; KEGG: hscC, chaperone protein HscC.
 0.992
Bccel_3709
PFAM: heat shock protein Hsp90; KEGG: Heat shock protein Hsp90-like protein.
  
 0.984
Bccel_5731
KEGG: hypothetical protein.
  
 0.958
grpE
Protein grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.948
Bccel_4366
PFAM: Clp domain protein; KEGG: ATP-dependent chaperone ClpB.
 
 
 0.916
Bccel_1219
PFAM: Rieske [2Fe-2S] iron-sulfur domain-containing protein; KEGG: glycine/D-amino acid oxidase, deaminating.
   
 0.867
Bccel_1449
CoA-disulfide reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, SirA-like domain-containing protein, Rhodanese-like protein, FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: NAD(FAD)-dependent dehydrogenase; SMART: Rhodanese-like protein; Belongs to the sulfur carrier protein TusA family.
  
 
 0.861
Bccel_1137
PFAM: Tetratricopeptide TPR_1 repeat-containing protein; KEGG: hypothetical protein.
  
 0.859
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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