STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bccel_5256TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated protein, Radical SAM domain protein; KEGG: tyrosine lyase ThiH; SMART: biotin and thiamin synthesis associated protein. (370 aa)    
Predicted Functional Partners:
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 0.999
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
 0.987
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.976
Bccel_5259
KEGG: thiamine biosynthesis protein ThiS; TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamine S protein.
 
 
 0.920
Bccel_5260
PFAM: UBA/THIF-type NAD/FAD binding protein, MoeZ/MoeB domain protein; KEGG: UBA/THIF-type NAD/FAD binding protein.
  
 0.857
Bccel_5061
KEGG: multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein, response regulator receiver, Hpt domain protein, histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein, histidine kinase A domain protein, response regulator receiver.
  
  
 0.833
Bccel_3661
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.815
Bccel_3689
KEGG: hypothetical protein.
  
 
 0.814
Bccel_0658
TIGRFAM: [FeFe]-hydrogenase maturation HydG, radical SAM; PFAM: biotin and thiamin synthesis associated protein, Radical SAM domain protein; KEGG: iron-only hydrogenase maturation protein HydG; SMART: biotin and thiamin synthesis associated protein, Elongator protein 3/MiaB/NifB.
  
  
 
0.812
Bccel_0661
KEGG: hydrogenase maturation GTPase HydF; TIGRFAM: [FeFe]-hydrogenase H-cluster maturation GTPase HydF, small GTP-binding protein; PFAM: GTP1/OBG protein.
   
 0.776
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.