STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bccel_5667PFAM: DNA gyrase/topoisomerase IV subunit A; KEGG: type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; SMART: DNA gyrase/topoisomerase IV subunit A. (727 aa)    
Predicted Functional Partners:
Bccel_5668
KEGG: type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein, TOPRIM domain-containing protein, DNA gyrase subunit B domain protein; SMART: DNA topoisomerase II.
 
 0.998
gyrB
DNA gyrase B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
 0.995
metG-2
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.794
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
  
 0.777
Bccel_3896
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
    
 
 0.766
Bccel_3900
KEGG: flgL, flagellar hook-associated protein 3; TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein.
    
 
 0.766
fliE
TIGRFAM: flagellar hook-basal body complex subunit FliE; HAMAP : Flagellar hook-basal body complex protein fliE; KEGG: flagellar hook-basal body complex protein FliE; PFAM: flagellar hook-basal body complex protein FliE.
    
 
 0.757
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.736
Bccel_2599
PFAM: Flagellar protein FlgJ; KEGG: Rod binding protein.
    
   0.724
Bccel_3651
Flagellar hook capping protein; Required for flagellar hook formation. May act as a scaffolding protein.
    
   0.724
Your Current Organism:
Pseudobacteroides cellulosolvens
NCBI taxonomy Id: 398512
Other names: Bacteroides cellulosolvens ATCC 35603, Bacteroides cellulosolvens DSM 2933, P. cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933, Pseudobacteroides cellulosolvens DSM 2933 = ATCC 35603
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