STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (342 aa)    
Predicted Functional Partners:
ACD15489.1
PFAM: Uroporphyrinogen III synthase HEM4; protein of unknown function DUF513 hemX; KEGG: bxe:Bxe_A3410 bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase.
  
 0.999
ACD18003.1
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: bxe:Bxe_A0344 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.996
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 0.985
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
  
 0.979
ACD19363.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bxe:Bxe_B1649 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 0.970
ACD15394.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bxe:Bxe_A3659 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 0.960
ACD16389.1
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: bxe:Bxe_A2215 uroporphyrin-III C-methyltransferase.
  
 0.946
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: bxe:Bxe_A0896 glutamate-1-semialdehyde 2,1-aminomutase.
 
  
 0.886
ACD20724.1
PFAM: aminotransferase class-III; KEGG: rpd:RPD_2366 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.872
ACD15490.1
PFAM: HemY domain protein; Tetratricopeptide TPR_4; Tetratricopeptide TPR_2 repeat protein; KEGG: bxe:Bxe_A3409 hypothetical protein.
  
  
 0.852
Your Current Organism:
Paraburkholderia phytofirmans
NCBI taxonomy Id: 398527
Other names: Burkholderia phytofirmans PsJN, Burkholderia sp. PsJN, P. phytofirmans PsJN, Paraburkholderia phytofirmans PsJN
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