Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Daci_0332PFAM: peptidase M48 Ste24p; KEGG: aav:Aave_0280 peptidase M48, Ste24p. (305 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
    0.665
Daci_0331
PFAM: protein of unknown function DUF6 transmembrane; KEGG: ajs:Ajs_0201 protein of unknown function DUF6, transmembrane.
       0.649
Daci_0330
Transcriptional regulator, AraC family; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: ajs:Ajs_0200 cupin 2, conserved barrel domain protein.
     
 0.483
Daci_0329
PFAM: major facilitator superfamily MFS_1; KEGG: aav:Aave_0276 major facilitator superfamily MFS_1.
       0.478
Daci_1751
KEGG: yen:YE0990 AYP/GTP-binding protein.
   
   0.406
lpxA
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
    0.400
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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