STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Daci_0338NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (474 aa)    
Predicted Functional Partners:
Daci_0336
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: ajs:Ajs_3954 NAD(P)(+) transhydrogenase (AB-specific).
 0.999
Daci_0337
KEGG: ajs:Ajs_3952 NAD(P) transhydrogenase, subunit alpha part 2.
 
 0.999
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.936
nadE-2
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.936
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.906
cobB-2
PFAM: Silent information regulator protein Sir2; KEGG: ajs:Ajs_2262 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
    
  0.902
Daci_5608
TIGRFAM: cytidyltransferase-related domain protein; PFAM: NUDIX hydrolase; cytidylyltransferase; KEGG: ajs:Ajs_0701 cytidyltransferase-related domain.
    
  0.902
Daci_2460
TIGRFAM: release factor H-coupled RctB family protein; PFAM: protein of unknown function UPF0027; KEGG: pfl:PFL_2087 RtcB protein.
 
      0.636
Daci_1860
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: mpt:Mpe_A3709 NADH dehydrogenase (quinone).
  
  
 0.428
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.