STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Daci_0486Transcriptional regulator, MerR family; TIGRFAM: Hg(II)-responsive transcriptional regulator; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: ajs:Ajs_1301 putative transcriptional regulator, MerR family. (135 aa)    
Predicted Functional Partners:
merA
Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.900
Daci_0485
PFAM: Mercuric transport protein MerT; KEGG: ajs:Ajs_1300 mercuric transport protein MerT.
 
  
 0.894
merP
Mercuric transport protein periplasmic component; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
 
  
 0.881
Daci_2043
Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: gur:Gura_3524 putative transcriptional regulator, MerR family.
  
 
 
 0.789
Daci_6040
PFAM: regulatory protein MerR; KEGG: azo:azo1478 probable MerR-family transcriptional regulator.
  
     0.702
Daci_0487
Putative transcriptional regulator, ArsR family; SMART: regulatory protein ArsR; KEGG: mpt:Mpe_A2347 TC repressor.
     
 0.498
Daci_2984
PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ajs:Ajs_0639 heat shock protein DnaJ domain protein.
  
 
 0.484
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.484
Daci_0490
TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: har:HEAR1962 arsenite efflux pump ACR3.
     
 0.473
Daci_0488
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mpt:Mpe_A2346 hypothetical protein.
     
 0.461
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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