Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Daci_0486Transcriptional regulator, MerR family; TIGRFAM: Hg(II)-responsive transcriptional regulator; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: ajs:Ajs_1301 putative transcriptional regulator, MerR family. (135 aa)    
Predicted Functional Partners:
merP
Mercuric transport protein periplasmic component; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
 
  
 0.915
Daci_0485
PFAM: Mercuric transport protein MerT; KEGG: ajs:Ajs_1300 mercuric transport protein MerT.
 
  
 0.903
merA
Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.898
Daci_2043
Transcriptional regulator, MerR family; PFAM: regulatory protein MerR; Transcription regulator MerR DNA binding; KEGG: gur:Gura_3524 putative transcriptional regulator, MerR family.
  
 
 
 0.784
Daci_6040
PFAM: regulatory protein MerR; KEGG: azo:azo1478 probable MerR-family transcriptional regulator.
  
     0.702
Daci_0487
Putative transcriptional regulator, ArsR family; SMART: regulatory protein ArsR; KEGG: mpt:Mpe_A2347 TC repressor.
     
 0.499
Daci_0490
TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: har:HEAR1962 arsenite efflux pump ACR3.
     
 0.471
Daci_0488
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: mpt:Mpe_A2346 hypothetical protein.
     
 0.457
Daci_0489
PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: mpt:Mpe_A2345 arsenate reductase, putative.
     
 0.454
Daci_0491
TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: har:HEAR1960 arsenate reductase (glutaredoxin).
  
  
 0.449
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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