STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Daci_0845KEGG: rso:RSp1185 probable D-serine deaminase (d-serine dehydratase) protein. (424 aa)    
Predicted Functional Partners:
Daci_0116
TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: ajs:Ajs_0080 threonine dehydratase.
    
 0.903
Daci_3585
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pen:PSEEN2008 L-serine dehydratase.
    
 0.903
ilvA
Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
    
 0.903
Daci_3939
KEGG: aav:Aave_2791 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
   
 
  0.806
Daci_3777
KEGG: ajs:Ajs_2044 lactoylglutathione lyase.
   
 
  0.805
Daci_4738
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: vei:Veis_2069 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
     
 0.803
Daci_0293
PFAM: Aldehyde Dehydrogenase; KEGG: mpt:Mpe_A0361 lactaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
  0.800
Daci_1407
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: reh:H16_B0841 D-3-phosphoglycerate dehydrogenase.
     
  0.800
Daci_2046
PFAM: ThiJ/PfpI domain protein; KEGG: pfo:Pfl_2246 ThiJ/PfpI.
     
  0.800
Daci_5635
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rsh:Rsph17029_3087 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
     
  0.800
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.