STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrCDihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (346 aa)    
Predicted Functional Partners:
pyrB
TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: ajs:Ajs_3570 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.985
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.979
Daci_1582
PFAM: amidohydrolase; KEGG: ajs:Ajs_3569 amidohydrolase.
    
 0.921
Daci_2862
TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate dehydrogenase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: aav:Aave_0967 dihydroorotate dehydrogenase family protein.
  
  
 0.781
Daci_1387
KEGG: aav:Aave_4317 putative transmembrane protein.
       0.780
htpX
PFAM: peptidase M48 Ste24p; HtpX domain protein; KEGG: aav:Aave_4316 peptidase M48, Ste24p; Belongs to the peptidase M48B family.
       0.780
Daci_1386
PFAM: protein of unknown function DUF88; KEGG: aav:Aave_4318 protein of unknown function DUF88.
 
     0.763
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: ajs:Ajs_2390 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
   
  
 0.721
Daci_0219
Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pol:Bpro_0563 periplasmic sensor hybrid histidine kinase.
   
    0.633
carA
TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: aav:Aave_2610 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family.
   
  
 0.609
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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