Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: ajs:Ajs_3581 glutamate-1-semialdehyde-2,1-aminomutase. (438 aa)    
Predicted Functional Partners:
Daci_0380
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: aav:Aave_0327 porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.993
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.990
Daci_4755
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: aav:Aave_3732 beta-ketoacyl synthase.
    
 0.949
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.942
Daci_2368
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: ajs:Ajs_2843 uroporphyrin-III C-methyltransferase.
 
   
 0.831
Daci_3069
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; cytochrome c biogenesis protein transmembrane region; Redoxin domain protein; KEGG: bch:Bcen2424_6244 cytochrome c biogenesis protein, transmembrane region.
  
  
 0.772
Daci_1570
PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: aav:Aave_0899 phosphomethylpyrimidine kinase type-1.
  
  
 0.770
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.750
Daci_2937
PFAM: AMP-dependent synthetase and ligase; KEGG: bbr:BB4380 putative D-alanine-D-alanyl carrier protein ligase.
 
  
 0.697
Daci_4753
TIGRFAM: non-ribosomal peptide synthase; amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; condensation domain protein; phosphopantetheine-binding; KEGG: bbt:BBta_6813 arthrofactin synthetase/syringopeptin synthetase C-related non-ribosomal peptide synthetase.
     
 0.639
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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