Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bioF8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (405 aa)    
Predicted Functional Partners:
Daci_1834
TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: aav:Aave_3841 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.997
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
  
 0.995
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.945
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
   
 0.794
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
 
 
 0.766
Daci_4755
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: aav:Aave_3732 beta-ketoacyl synthase.
  
 
 0.750
Daci_1831
PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: ajs:Ajs_3495 5-carboxymethyl-2-hydroxymuconate isomerase.
       0.683
Daci_1830
PFAM: DTW domain containing protein; KEGG: ajs:Ajs_1957 DTW domain containing protein.
       0.666
Daci_6020
Beta-alanine--pyruvate transaminase; PFAM: aminotransferase class-III; KEGG: ajs:Ajs_4103 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.648
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
 
 0.641
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
Server load: medium (46%) [HD]