Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Daci_1992TIGRFAM: sulfoacetaldehyde acetyltransferase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: vei:Veis_3999 thiamine pyrophosphate enzyme domain protein TPP-binding; Belongs to the TPP enzyme family. (603 aa)    
Predicted Functional Partners:
Daci_2019
PFAM: FAD dependent oxidoreductase; KEGG: bxe:Bxe_B0685 putative taurine dehydrogenase, large subunit.
  
  
 0.977
Daci_2020
PFAM: protein of unknown function DUF1486; KEGG: reh:H16_B1892 hypothetical protein.
 
  
 0.971
Daci_0755
PFAM: phosphate acetyl/butaryl transferase; MaoC domain protein dehydratase; KEGG: pla:Plav_3451 phosphate butyryltransferase.
  
 0.937
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.910
Daci_1995
Cobaltochelatase; PFAM: Cobalt chelatase CobT subunit; KEGG: reu:Reut_B3756 CobT protein.
 
     0.843
Daci_4866
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: aav:Aave_3111 acetolactate synthase, small subunit.
 
 
 0.829
Daci_1993
PFAM: regulatory protein IclR; Transcriptional regulator IclR; KEGG: reu:Reut_B3754 regulatory protein, IclR.
 
     0.771
Daci_1991
PFAM: phosphate acetyl/butaryl transferase; KEGG: acr:Acry_3031 phosphate butyryltransferase.
  
 
 0.752
Daci_1994
Cobaltochelatase; KEGG: reu:Reut_B3755 putative MoxR-like ATPase; PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
 
     0.746
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
  
 0.716
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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