| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Daci_2026 | Daci_2029 | Daci_2026 | Daci_2029 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | 0.546 |
| Daci_2026 | Daci_2030 | Daci_2026 | Daci_2030 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: ajs:Ajs_0925 protein kinase. | 0.426 |
| Daci_2026 | Daci_2031 | Daci_2026 | Daci_2031 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: ajs:Ajs_0924 protein phosphatase 2C domain protein. | 0.410 |
| Daci_2026 | Daci_2032 | Daci_2026 | Daci_2032 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.459 |
| Daci_2026 | Daci_2033 | Daci_2026 | Daci_2033 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.456 |
| Daci_2026 | gmk | Daci_2026 | Daci_2028 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.962 |
| Daci_2026 | rpoZ | Daci_2026 | Daci_2027 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.736 |
| Daci_2029 | Daci_2026 | Daci_2029 | Daci_2026 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.546 |
| Daci_2029 | Daci_2030 | Daci_2029 | Daci_2030 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: ajs:Ajs_0925 protein kinase. | 0.591 |
| Daci_2029 | Daci_2031 | Daci_2029 | Daci_2031 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: ajs:Ajs_0924 protein phosphatase 2C domain protein. | 0.590 |
| Daci_2029 | Daci_2032 | Daci_2029 | Daci_2032 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.512 |
| Daci_2029 | Daci_2033 | Daci_2029 | Daci_2033 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.504 |
| Daci_2029 | Daci_5558 | Daci_2029 | Daci_5558 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: ajs:Ajs_0741 glutamate synthase (ferredoxin). | 0.728 |
| Daci_2029 | coaD | Daci_2029 | Daci_1803 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.597 |
| Daci_2029 | gmk | Daci_2029 | Daci_2028 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.931 |
| Daci_2029 | rpoZ | Daci_2029 | Daci_2027 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.884 |
| Daci_2030 | Daci_2026 | Daci_2030 | Daci_2026 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: ajs:Ajs_0925 protein kinase. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.426 |
| Daci_2030 | Daci_2029 | Daci_2030 | Daci_2029 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: ajs:Ajs_0925 protein kinase. | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ajs:Ajs_0926 domain of unknown function DUF1732. | 0.591 |
| Daci_2030 | Daci_2031 | Daci_2030 | Daci_2031 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: ajs:Ajs_0925 protein kinase. | PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: ajs:Ajs_0924 protein phosphatase 2C domain protein. | 0.968 |
| Daci_2030 | Daci_2032 | Daci_2030 | Daci_2032 | PFAM: protein kinase; SMART: tyrosine protein kinase; serine/threonine protein kinase; KEGG: ajs:Ajs_0925 protein kinase. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.625 |