STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Daci_2147Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (454 aa)    
Predicted Functional Partners:
Daci_5909
KEGG: mpt:Mpe_A0798 xanthine dehydrogenase; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit; PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding.
 
 
 0.974
Daci_5910
TIGRFAM: xanthine dehydrogenase, small subunit; PFAM: ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein; KEGG: mpt:Mpe_A0799 putative xanthine dehydrogenase (subunit A) oxidoreductase protein.
 
  
  0.969
Daci_2513
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
  
 
0.927
Daci_3816
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: aav:Aave_1485 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding.
  
 
 0.910
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.910
Daci_3817
PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: aav:Aave_1486 molybdopterin dehydrogenase, FAD-binding.
  
 
 0.908
Daci_3818
PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: rle:pRL120302 putative xanthine dehydrogenase YagT iron-sulfur binding subunit.
  
 
 0.908
ppnP
Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
Daci_2127
TIGRFAM: xanthine dehydrogenase accessory protein XdhC; PFAM: protein of unknown function DUF182; KEGG: pna:Pnap_1013 protein of unknown function DUF182.
 
 
 0.874
Daci_2121
TIGRFAM: hydroxyisourate hydrolase; PFAM: Transthyretin; KEGG: ajs:Ajs_1123 transthyretin; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
   
 0.789
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
Server load: low (32%) [HD]