STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
flhCFlagellar transcriptional activator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (180 aa)    
Predicted Functional Partners:
flhD
Flagellar transcriptional activator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
 
 
 0.999
Daci_0603
PFAM: OmpA/MotB domain protein; KEGG: aav:Aave_4409 OmpA/MotB domain protein.
 
  
 0.847
Daci_0604
PFAM: MotA/TolQ/ExbB proton channel; KEGG: ajs:Ajs_3815 MotA/TolQ/ExbB proton channel.
 
    0.815
Daci_0621
KEGG: ajs:Ajs_3809 flagellar protein FliT.
 
   
 0.746
Daci_0634
SAF domain; KEGG: aav:Aave_4419 SAF domain.
  
  
 0.715
lexA
Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
      
 0.705
Daci_0644
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
   
 0.683
Daci_3845
TIGRFAM: type IV / VI secretion system protein, DotU family; type VI secretion system OmpA/MotB family protein; PFAM: OmpA/MotB domain protein; KEGG: aav:Aave_1472 OmpA/MotB domain protein.
  
  
 0.681
Daci_0625
KEGG: aav:Aave_4429 flagellar rod assembly protein/muramidase FlgJ; TIGRFAM: flagellar rod assembly protein/muramidase FlgJ; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2.
  
   
 0.661
Daci_1324
PFAM: regulatory protein TetR; KEGG: aav:Aave_4136 transcriptional regulator, TetR family.
  
     0.615
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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