Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Daci_2387PFAM: histone deacetylase superfamily; KEGG: aav:Aave_2164 histone deacetylase superfamily. (317 aa)    
Predicted Functional Partners:
Daci_2298
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: reu:Reut_C6418 AAA ATPase, central region.
   
 0.926
Daci_0883
PFAM: nuclear protein SET; KEGG: ajs:Ajs_3991 nuclear protein SET.
 
 0.899
Daci_5705
PFAM: Calcium-binding EF-hand-containing protein; KEGG: aav:Aave_3976 putative signal transduction protein with EFhand domain.
    
 0.885
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
    
 0.859
Daci_2984
PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ajs:Ajs_0639 heat shock protein DnaJ domain protein.
 
 0.819
atpD
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
    
 0.812
pcp
Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family.
    
 
 0.811
Daci_1174
TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: sme:SMc01870 probable aquaporin Z (bacterial nodulin-like intrinsic) transmembrane protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
   0.806
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 
 0.803
Daci_2504
Peptidyl-prolyl cis-trans isomerase cyclophilin type; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.795
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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