Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Daci_2460TIGRFAM: release factor H-coupled RctB family protein; PFAM: protein of unknown function UPF0027; KEGG: pfl:PFL_2087 RtcB protein. (384 aa)    
Predicted Functional Partners:
Daci_2459
TIGRFAM: peptide chain release factor H; PFAM: Class I peptide chain release factor; KEGG: bur:Bcep18194_A4861 class I peptide chain release factor.
 
  
 0.931
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
  
 0.855
Daci_0679
KEGG: bam:Bamb_5431 nucleotidyltransferase-like protein.
 
    0.735
Daci_0675
PFAM: sigma-54 factor interaction domain-containing protein; regulator of RNA terminal phosphate cyclase; SMART: AAA ATPase; KEGG: pna:Pnap_0497 regulator of RNA terminal phosphate cyclase.
 
  
 0.711
Daci_0676
PFAM: band 7 protein; KEGG: pol:Bpro_1471 band 7 protein.
 
 
 0.670
Daci_0336
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: ajs:Ajs_3954 NAD(P)(+) transhydrogenase (AB-specific).
 
      0.639
Daci_0338
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
 
      0.636
kptA
Phosphate acetyltransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase.
  
     0.543
Daci_4559
KEGG: pfl:PFL_3007 homolog of eukaryotic DNA ligase III.
  
   
 0.538
Daci_2155
PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: ajs:Ajs_1132 DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family.
   
 0.459
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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