Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gshATIGRFAM: glutamate--cysteine ligase; KEGG: ajs:Ajs_2521 glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (509 aa)    
Predicted Functional Partners:
gshB
KEGG: ajs:Ajs_3907 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
  
 
 0.942
Daci_3264
TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: aav:Aave_1844 aminopeptidase N.
     
 0.917
Daci_0780
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: aav:Aave_0589 gamma-glutamyltransferase.
    
 0.908
Daci_1435
KEGG: aav:Aave_3307 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
    
 0.908
Daci_2120
KEGG: aav:Aave_1114 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
    
 0.908
Daci_3783
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: ret:RHE_CH02146 gamma-glutamyltranspeptidase protein.
    
 0.908
Daci_4564
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: pol:Bpro_3878 gamma-glutamyltransferase.
    
 0.908
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
 0.907
Daci_4427
PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: rru:Rru_A0138 leucyl aminopeptidase; Belongs to the peptidase M17 family.
     
 0.907
Daci_0718
Glutamate--cysteine ligase GCS2; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
 0.904
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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