Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aroQ3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (147 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 0.961
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
 
 0.937
aroQ-2
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
  
  
 
0.910
Daci_2493
PFAM: Class I peptide chain release factor; KEGG: ajs:Ajs_1612 class I peptide chain release factor.
       0.814
Daci_2492
PFAM: alpha/beta hydrolase fold; KEGG: aav:Aave_2303 alpha/beta hydrolase fold.
       0.773
Daci_4437
PFAM: UBA/THIF-type NAD/FAD binding protein; Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: reu:Reut_B5029 shikimate 5-dehydrogenase.
  
 
 0.613
Daci_2494
PFAM: Extradiol ring-cleavage dioxygenase class III protein subunit B; KEGG: ajs:Ajs_1613 extradiol ring-cleavage dioxygenase, class III enzyme, subunit B.
       0.563
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
  
  
 0.562
Daci_4721
TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; amino acid-binding ACT domain protein; KEGG: ajs:Ajs_2466 chorismate mutase.
     
 0.550
Daci_5181
Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.
  
    0.528
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.