Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Daci_2513Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (475 aa)    
Predicted Functional Partners:
Daci_5909
KEGG: mpt:Mpe_A0798 xanthine dehydrogenase; TIGRFAM: xanthine dehydrogenase, molybdopterin binding subunit; PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding.
 
 
 0.945
Daci_5910
TIGRFAM: xanthine dehydrogenase, small subunit; PFAM: ferredoxin; molybdopterin dehydrogenase FAD-binding; [2Fe-2S]-binding domain protein; CO dehydrogenase flavoprotein domain protein; KEGG: mpt:Mpe_A0799 putative xanthine dehydrogenase (subunit A) oxidoreductase protein.
 
 
  0.932
Daci_2147
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
  
 
0.927
Daci_3816
PFAM: aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; KEGG: aav:Aave_1485 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding.
  
 
 0.912
Daci_3818
PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: rle:pRL120302 putative xanthine dehydrogenase YagT iron-sulfur binding subunit.
  
 
 0.912
Daci_3817
PFAM: molybdopterin dehydrogenase FAD-binding; KEGG: aav:Aave_1486 molybdopterin dehydrogenase, FAD-binding.
  
 
 0.910
ppnP
Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
 0.902
Daci_3598
PFAM: protein of unknown function DUF152; KEGG: vei:Veis_3820 protein of unknown function DUF152; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.900
Daci_2514
PFAM: Xanthine/uracil/vitamin C permease; KEGG: lbr:LVIS_1044 xanthine/uracil permease.
 
  
 0.870
Daci_2512
PFAM: pseudouridine synthase; KEGG: ajs:Ajs_1183 pseudouridine synthase; Belongs to the pseudouridine synthase RsuA family.
       0.714
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.