Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (365 aa)    
Predicted Functional Partners:
Daci_0381
PFAM: conserved hypothetical protein; KEGG: ajs:Ajs_0268 conserved hypothetical protein 701.
 
  
 0.958
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
     
 0.937
Daci_5745
KEGG: bvi:Bcep1808_1603 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase.
  
 
 0.923
Daci_4784
KEGG: ajs:Ajs_4093 twin-arginine translocation pathway signal.
  
 
 0.913
Daci_0888
PFAM: Rubrerythrin; Ferritin Dps family protein; KEGG: aav:Aave_3866 ferritin, Dps family protein.
     
 0.912
Daci_2757
Bacterioferritin; Iron-storage protein.
     
 0.912
Daci_5073
Bacterioferritin; Iron-storage protein.
     
 0.912
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.911
Daci_4546
PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: pna:Pnap_2042 pyridoxamine 5'-phosphate oxidase-related, FMN-binding.
     
 0.907
cyaY
Iron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
    
 
 0.837
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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