Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
Daci_2673PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rme:Rmet_2992 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (327 aa)    
Predicted Functional Partners:
Daci_2675
TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; SMART: extracellular solute-binding protein family 3; KEGG: rme:Rmet_2994 phosphonate-binding periplasmic protein.
 
   
 0.852
phnC-2
Phosphonate ABC transporter, ATPase subunit; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
 
     0.839
Daci_2674
TIGRFAM: phosphonate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: rme:Rmet_2993 phosphonate uptake transporter.
 
     0.817
Daci_5635
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rsh:Rsph17029_3087 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
     0.728
Daci_5969
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ajs:Ajs_3758 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding.
 
     0.647
Daci_2677
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: rme:Rmet_2996 transcriptional regulator, LysR family.
       0.495
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
  
   0.409
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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