| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Daci_2846 | Daci_3052 | Daci_2846 | Daci_3052 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | 0.917 |
| Daci_2846 | Daci_4503 | Daci_2846 | Daci_4503 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: pfl:PFL_2830 aspartate racemase. | 0.906 |
| Daci_2846 | Daci_4864 | Daci_2846 | Daci_4864 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | KEGG: ajs:Ajs_1772 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.906 |
| Daci_2846 | glyA | Daci_2846 | Daci_3707 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.926 |
| Daci_2846 | glyA-2 | Daci_2846 | Daci_3712 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.926 |
| Daci_2846 | glyA-3 | Daci_2846 | Daci_4955 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.926 |
| Daci_2846 | serC | Daci_2846 | Daci_4720 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.965 |
| Daci_2846 | trpA | Daci_2846 | Daci_5244 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.906 |
| Daci_2846 | trpB | Daci_2846 | Daci_3688 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.924 |
| Daci_2846 | trpB-2 | Daci_2846 | Daci_5243 | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.924 |
| Daci_3052 | Daci_2846 | Daci_3052 | Daci_2846 | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | 0.917 |
| Daci_3052 | Daci_4503 | Daci_3052 | Daci_4503 | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: pfl:PFL_2830 aspartate racemase. | 0.900 |
| Daci_3052 | Daci_4864 | Daci_3052 | Daci_4864 | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | KEGG: ajs:Ajs_1772 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| Daci_3052 | glyA | Daci_3052 | Daci_3707 | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |
| Daci_3052 | glyA-2 | Daci_3052 | Daci_3712 | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |
| Daci_3052 | glyA-3 | Daci_3052 | Daci_4955 | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |
| Daci_3052 | trpA | Daci_3052 | Daci_5244 | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.914 |
| Daci_3052 | trpB | Daci_3052 | Daci_3688 | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.907 |
| Daci_3052 | trpB-2 | Daci_3052 | Daci_5243 | Serine--glyoxylate transaminase; PFAM: aminotransferase class V; KEGG: pol:Bpro_2753 aminotransferase, class V. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.907 |
| Daci_4503 | Daci_2846 | Daci_4503 | Daci_2846 | TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: pfl:PFL_2830 aspartate racemase. | KEGG: aav:Aave_1576 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase; HAD-superfamily hydrolase subfamily IB hypothetical 1; Haloacid dehalogenase domain protein hydrolase type 3. | 0.906 |