STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Daci_2984PFAM: heat shock protein DnaJ domain protein; chaperone DnaJ domain protein; KEGG: ajs:Ajs_0639 heat shock protein DnaJ domain protein. (331 aa)    
Predicted Functional Partners:
Daci_2983
KEGG: ajs:Ajs_0638 transcriptional regulatory protein, MerR family.
 
 
 0.992
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 0.954
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.954
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 0.904
Daci_1860
PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: mpt:Mpe_A3709 NADH dehydrogenase (quinone).
   
 
 0.867
Daci_3774
2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: aav:Aave_4256 heat shock protein 70.
 0.848
Daci_1433
2-alkenal reductase; PFAM: Heat shock protein 70; KEGG: rso:RSp0521 probable chaperone transmembrane protein.
 0.839
rplQ
PFAM: ribosomal protein L17; KEGG: ajs:Ajs_0407 ribosomal protein L17.
  
 
 0.823
hscA
Fe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
 0.822
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
 
 0.817
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.