STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Daci_3003Secreted repeat-domain containing protein; PFAM: Secreted repeat of unknown function; KEGG: ajs:Ajs_2553 secreted repeat of unknown function. (138 aa)    
Predicted Functional Partners:
Daci_3001
KEGG: ajs:Ajs_2555 putative transmembrane anti-sigma factor.
 
     0.916
Daci_3002
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: ajs:Ajs_2554 RNA polymerase, sigma-24 subunit, ECF subfamily.
 
     0.747
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.516
Daci_3005
PFAM: cyclase/dehydrase; KEGG: aav:Aave_3373 cyclase/dehydrase.
       0.499
Daci_3006
PFAM: protein of unknown function UPF0125; KEGG: aav:Aave_3372 protein of unknown function UPF0125; Belongs to the UPF0125 (RnfH) family.
       0.438
Daci_3577
PFAM: major facilitator superfamily MFS_1; KEGG: pfl:PFL_4098 transporter, putative.
  
     0.420
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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