Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Daci_3070TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; KEGG: bra:BRADO5066 peptide methionine sulfoxide reductase MsrB. (166 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.995
msrA-2
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.988
Daci_3069
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; cytochrome c biogenesis protein transmembrane region; Redoxin domain protein; KEGG: bch:Bcen2424_6244 cytochrome c biogenesis protein, transmembrane region.
 
 0.916
Daci_0587
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: aav:Aave_4456 cytochrome c biogenesis protein, transmembrane region.
   
 
 0.719
Daci_3072
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: bam:Bamb_5784 periplasmic sensor signal transduction histidine kinase.
       0.531
Daci_2654
Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
   
  
 0.517
Daci_3071
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bur:Bcep18194_C6809 two component transcriptional regulator, winged helix family.
       0.514
Daci_3067
TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: mpt:Mpe_A2526 CHR transporter.
     
 0.473
Daci_2426
TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: ajs:Ajs_2794 succinate dehydrogenase, cytochrome b subunit.
   
    0.471
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.462
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.