Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Daci_3287Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SMART: regulatory protein Crp; KEGG: aav:Aave_3075 transcriptional regulator, Crp/Fnr family. (239 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.743
rpoD
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.726
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.641
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.640
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.621
Daci_3286
PFAM: aminoglycoside phosphotransferase; KEGG: ajs:Ajs_1778 aminoglycoside phosphotransferase.
     
 0.581
Daci_3288
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: aav:Aave_3073 3-hydroxybutyryl-CoA dehydrogenase.
  
    0.486
Daci_3285
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: aav:Aave_3077 acyl-CoA dehydrogenase domain protein.
       0.476
Daci_4365
PFAM: protein kinase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; tyrosine protein kinase; serine/threonine protein kinase; KEGG: aav:Aave_3066 serine/threonine protein kinase.
  
 
 0.465
Daci_1174
TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: sme:SMc01870 probable aquaporin Z (bacterial nodulin-like intrinsic) transmembrane protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 0.460
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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