Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Daci_3292TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: aav:Aave_3069 thiamine biosynthesis protein ThiS. (65 aa)    
Predicted Functional Partners:
thiG
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 
 0.998
Daci_3290
KEGG: aav:Aave_3071 thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase.
 
  
 0.990
thiC
Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.943
Daci_3293
PFAM: FAD dependent oxidoreductase; KEGG: aav:Aave_3068 FAD dependent oxidoreductase.
 
  
 0.930
Daci_1811
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aav:Aave_3860 UBA/ThiF-type NAD/FAD binding protein.
  
 
 0.924
Daci_3294
KEGG: ajs:Ajs_1787 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
  
  
 0.894
Daci_1570
PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: aav:Aave_0899 phosphomethylpyrimidine kinase type-1.
  
  
 0.834
Daci_6032
KEGG: ajs:Ajs_4108 hypothetical protein.
 
     0.586
Daci_1710
PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: aav:Aave_1150 histone family protein nucleoid-structuring protein H-NS.
  
     0.506
Daci_4401
PFAM: major facilitator superfamily MFS_1; KEGG: aav:Aave_4589 major facilitator superfamily MFS_1.
  
     0.475
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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