STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Daci_3412PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sfr:Sfri_3571 CMP/dCMP deaminase, zinc-binding. (144 aa)    
Predicted Functional Partners:
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
 0.955
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.947
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
    
 0.935
Daci_5725
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: aav:Aave_4022 5'-nucleotidase; Belongs to the 5'-nucleotidase family.
  
 
  0.904
surE
Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
Daci_5704
5'-nucleotidase; PFAM: 5-nucleotidase; KEGG: ajs:Ajs_0662 5-nucleotidase.
     
  0.900
Daci_3411
SMART: DNA-directed DNA polymerase; KEGG: xfa:XF0683 phage-related DNA polymerase.
     
 0.795
Daci_3410
KEGG: hit:NTHI1489 hypothetical protein.
 
     0.627
Daci_3413
Putative exonuclease RdgC; May be involved in recombination. Belongs to the RdgC family.
       0.590
Daci_3414
PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: pna:Pnap_3939 histone-like nucleoid-structuring protein H-NS.
       0.582
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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