Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobB-2PFAM: Silent information regulator protein Sir2; KEGG: ajs:Ajs_2262 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily. (284 aa)    
Predicted Functional Partners:
Daci_5608
TIGRFAM: cytidyltransferase-related domain protein; PFAM: NUDIX hydrolase; cytidylyltransferase; KEGG: ajs:Ajs_0701 cytidyltransferase-related domain.
  
 
  0.955
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.933
nadE-2
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.933
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.915
Daci_0336
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: ajs:Ajs_3954 NAD(P)(+) transhydrogenase (AB-specific).
     
 0.905
Daci_0337
KEGG: ajs:Ajs_3952 NAD(P) transhydrogenase, subunit alpha part 2.
     
 0.904
Daci_0338
NAD(P)(+) transhydrogenase (AB-specific); The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
    
  0.902
Daci_4026
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: rso:RS03880 putative transcription regulator protein.
  
  
 0.778
Daci_2387
PFAM: histone deacetylase superfamily; KEGG: aav:Aave_2164 histone deacetylase superfamily.
    
 0.776
Daci_0141
KEGG: aav:Aave_0181 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases.
  
 
 0.699
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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