| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Daci_0169 | Daci_0232 | Daci_0169 | Daci_0232 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.999 |
| Daci_0169 | Daci_1442 | Daci_0169 | Daci_1442 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aav:Aave_4297 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.833 |
| Daci_0169 | Daci_2550 | Daci_0169 | Daci_2550 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | PFAM: Methionine synthase vitamin-B12 independent; KEGG: aav:Aave_2779 methionine synthase, vitamin-B12 independent. | 0.969 |
| Daci_0169 | Daci_4038 | Daci_0169 | Daci_4038 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ajs:Ajs_2273 Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.944 |
| Daci_0169 | Daci_4832 | Daci_0169 | Daci_4832 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | KEGG: ajs:Ajs_2286 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.917 |
| Daci_0169 | Daci_4960 | Daci_0169 | Daci_4960 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | KEGG: ajs:Ajs_1656 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.917 |
| Daci_0169 | Daci_5156 | Daci_0169 | Daci_5156 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ajs:Ajs_3115 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.833 |
| Daci_0169 | Daci_5616 | Daci_0169 | Daci_5616 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | KEGG: pap:PSPA7_5762 homocysteine synthase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II. | 0.917 |
| Daci_0169 | ahcY | Daci_0169 | Daci_5919 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.943 |
| Daci_0169 | metZ | Daci_0169 | Daci_4768 | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.944 |
| Daci_0232 | Daci_0169 | Daci_0232 | Daci_0169 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homocysteine S-methyltransferase; KEGG: aav:Aave_0174 methionine synthase. | 0.999 |
| Daci_0232 | Daci_1442 | Daci_0232 | Daci_1442 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: aav:Aave_4297 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.827 |
| Daci_0232 | Daci_2550 | Daci_0232 | Daci_2550 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Methionine synthase vitamin-B12 independent; KEGG: aav:Aave_2779 methionine synthase, vitamin-B12 independent. | 0.940 |
| Daci_0232 | Daci_4038 | Daci_0232 | Daci_4038 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: ajs:Ajs_2273 Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.923 |
| Daci_0232 | Daci_4832 | Daci_0232 | Daci_4832 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: ajs:Ajs_2286 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase. | 0.918 |
| Daci_0232 | Daci_4960 | Daci_0232 | Daci_4960 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: ajs:Ajs_1656 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.918 |
| Daci_0232 | Daci_5156 | Daci_0232 | Daci_5156 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ajs:Ajs_3115 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. | 0.827 |
| Daci_0232 | Daci_5616 | Daci_0232 | Daci_5616 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: pap:PSPA7_5762 homocysteine synthase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II. | 0.918 |
| Daci_0232 | ahcY | Daci_0232 | Daci_5919 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.941 |
| Daci_0232 | metZ | Daci_0232 | Daci_4768 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | 0.923 |