Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Daci_4263KEGG: aav:Aave_2670 hypothetical protein. (294 aa)    
Predicted Functional Partners:
Daci_4262
KEGG: ajs:Ajs_1966 hypothetical protein.
 
  
 0.996
dnaE2
DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.967
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.881
Daci_1844
PFAM: Patatin; KEGG: aav:Aave_3832 patatin.
  
     0.573
lexA
Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
 
   
 0.568
Daci_5247
PFAM: peptidase S16 lon domain protein; KEGG: aav:Aave_1211 peptidase S16, lon domain protein.
 
     0.551
Daci_4264
PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: ajs:Ajs_1963 metal dependent phosphohydrolase.
       0.545
Daci_3501
KEGG: ajs:Ajs_1830 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein.
  
  
 0.506
Daci_4712
KEGG: bbr:BB2884 hypothetical protein.
  
     0.483
Daci_5958
PFAM: PEBP family protein; KEGG: aav:Aave_4694 PEBP family protein.
 
     0.460
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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