STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kuKu protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (325 aa)    
Predicted Functional Partners:
Daci_4339
TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, polymerase domain protein; DNA polymerase LigD, ligase domain protein; PFAM: DNA primase small subunit; ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: ajs:Ajs_2523 DNA ligase (ATP).
 
  
 0.986
Daci_4343
KEGG: aav:Aave_1492 putative DNA topoisomerase, type I.
 
    0.766
Daci_3044
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: aav:Aave_0375 ATP dependent DNA ligase.
 
  
 0.679
Daci_5983
KEGG: aav:Aave_4363 hypothetical protein.
 
     0.550
Daci_1807
PFAM: protein of unknown function DUF1328; KEGG: ajs:Ajs_3511 protein of unknown function DUF1328.
 
  
 0.548
Daci_5865
PFAM: conserved hypothetical protein; KEGG: aav:Aave_1446 hypothetical protein.
 
    0.529
Daci_5867
PFAM: protein of unknown function DUF1452; KEGG: bxe:Bxe_C0074 hypothetical protein.
 
  
 0.467
Daci_4342
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
 
    0.447
Daci_4028
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: ajs:Ajs_2265 3-demethylubiquinone-9 3-methyltransferase.
  
     0.438
Daci_4341
KEGG: tet:TTHERM_00163900 Bifunctional endo-1,4-beta-xylanase xylA precursor, putative PROSITE: ASN_RICH GLN_RICH.
       0.436
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.