Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Daci_4424PFAM: protein of unknown function DUF156; KEGG: aha:AHA_0625 hypothetical protein. (81 aa)    
Predicted Functional Partners:
Daci_4425
TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pae:PA1297 probable metal transporter.
 
  
 0.784
Daci_2414
TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: ajs:Ajs_2800 alcohol dehydrogenase, zinc-binding domain protein; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
  
 0.681
Daci_0183
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sme:SMc03929 putative zinc-type alcohol dehydrogenase transmembrane protein.
  
  
 0.622
Daci_2413
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
  
  
 0.583
Daci_2656
PFAM: putative esterase; KEGG: bte:BTH_II1456 esterase, putative.
  
  
 0.553
Daci_0464
TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: pde:Pden_3353 cation diffusion facilitator family transporter.
 
  
 0.520
merA
Mercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.464
Daci_4423
PFAM: protein of unknown function DUF559; KEGG: rfr:Rfer_3040 DNA helicase related protein.
       0.446
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.425
merP
Mercuric transport protein periplasmic component; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
 
  
 0.408
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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