Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fur-2Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: vei:Veis_3389 ferric uptake regulator, Fur family; Belongs to the Fur family. (141 aa)    
Predicted Functional Partners:
fur
Ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; KEGG: rme:Rmet_2976 ferric uptake regulator, FUR family; Belongs to the Fur family.
  
     0.673
Daci_5072
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.572
Daci_0161
PFAM: zinc finger SWIM domain protein; KEGG: hch:HCH_03960 protein containing SWIM zinc finger domain.
  
    0.513
Daci_4905
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: aav:Aave_2639 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.507
Daci_0584
KEGG: ajs:Ajs_3857 CoA-binding domain protein.
  
    0.459
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.448
rpoH
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
  
 
 0.404
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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