node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Daci_0959 | Daci_4866 | Daci_0959 | Daci_4866 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reu:Reut_B3575 hypothetical protein; Belongs to the TPP enzyme family. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: aav:Aave_3111 acetolactate synthase, small subunit. | 0.914 |
Daci_0959 | Daci_5831 | Daci_0959 | Daci_5831 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reu:Reut_B3575 hypothetical protein; Belongs to the TPP enzyme family. | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: vei:Veis_0037 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.556 |
Daci_0959 | ilvC | Daci_0959 | Daci_4865 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reu:Reut_B3575 hypothetical protein; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.971 |
Daci_0959 | ilvD | Daci_0959 | Daci_2450 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reu:Reut_B3575 hypothetical protein; Belongs to the TPP enzyme family. | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: swi:Swit_1660 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.779 |
Daci_0959 | ilvD-2 | Daci_0959 | Daci_2756 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reu:Reut_B3575 hypothetical protein; Belongs to the TPP enzyme family. | KEGG: aav:Aave_1506 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.666 |
Daci_0959 | ilvD-3 | Daci_0959 | Daci_3009 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reu:Reut_B3575 hypothetical protein; Belongs to the TPP enzyme family. | KEGG: ajs:Ajs_1071 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.719 |
Daci_0959 | leuC | Daci_0959 | Daci_5235 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reu:Reut_B3575 hypothetical protein; Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.513 |
Daci_1020 | Daci_4866 | Daci_1020 | Daci_4866 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent); Belongs to the TPP enzyme family. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: aav:Aave_3111 acetolactate synthase, small subunit. | 0.939 |
Daci_1020 | Daci_5831 | Daci_1020 | Daci_5831 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent); Belongs to the TPP enzyme family. | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: vei:Veis_0037 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.748 |
Daci_1020 | ilvC | Daci_1020 | Daci_4865 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent); Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.982 |
Daci_1020 | ilvD | Daci_1020 | Daci_2450 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent); Belongs to the TPP enzyme family. | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: swi:Swit_1660 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.832 |
Daci_1020 | ilvD-2 | Daci_1020 | Daci_2756 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent); Belongs to the TPP enzyme family. | KEGG: aav:Aave_1506 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.705 |
Daci_1020 | ilvD-3 | Daci_1020 | Daci_3009 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent); Belongs to the TPP enzyme family. | KEGG: ajs:Ajs_1071 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.813 |
Daci_1020 | leuC | Daci_1020 | Daci_5235 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: reh:H16_B0313 acetolactate synthase large subunit (TPP dependent); Belongs to the TPP enzyme family. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.608 |
Daci_2284 | Daci_4866 | Daci_2284 | Daci_4866 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bbr:BB0337 hypothetical protein; Belongs to the TPP enzyme family. | TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: aav:Aave_3111 acetolactate synthase, small subunit. | 0.950 |
Daci_2284 | Daci_5831 | Daci_2284 | Daci_5831 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bbr:BB0337 hypothetical protein; Belongs to the TPP enzyme family. | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: vei:Veis_0037 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.791 |
Daci_2284 | ilvC | Daci_2284 | Daci_4865 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bbr:BB0337 hypothetical protein; Belongs to the TPP enzyme family. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.981 |
Daci_2284 | ilvD | Daci_2284 | Daci_2450 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bbr:BB0337 hypothetical protein; Belongs to the TPP enzyme family. | PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; KEGG: swi:Swit_1660 dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.821 |
Daci_2284 | ilvD-2 | Daci_2284 | Daci_2756 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bbr:BB0337 hypothetical protein; Belongs to the TPP enzyme family. | KEGG: aav:Aave_1506 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.738 |
Daci_2284 | ilvD-3 | Daci_2284 | Daci_3009 | PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bbr:BB0337 hypothetical protein; Belongs to the TPP enzyme family. | KEGG: ajs:Ajs_1071 dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family. | 0.822 |