STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Daci_4972PFAM: metallophosphoesterase; KEGG: sma:SAV2323 putative serine/threonine protein phosphatase. (360 aa)    
Predicted Functional Partners:
Daci_1190
PFAM: major facilitator superfamily MFS_1; KEGG: ajs:Ajs_2346 major facilitator superfamily MFS_1.
  
     0.559
Daci_4971
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.541
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.508
Daci_1318
PFAM: glycosyl transferase family 2; methyltransferase small; Methionine biosynthesis MetW protein; Methyltransferase type 11; Methyltransferase type 12; KEGG: aav:Aave_4142 glycosyl transferase, family 2.
   
   0.504
Daci_0609
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pfl:PFL_3447 hypothetical protein.
   
   0.485
Daci_1316
PFAM: Methyltransferase type 12; KEGG: aav:Aave_4143 methyltransferase type 12.
   
   0.485
Daci_4070
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pae:PA2650 hypothetical protein.
   
   0.485
ubiG
Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
   
   0.485
Your Current Organism:
Delftia acidovorans
NCBI taxonomy Id: 398578
Other names: D. acidovorans SPH-1, Delftia acidovorans SPH-1, Delftia acidovorans str. SPH-1, Delftia acidovorans strain SPH-1
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