node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Daci_0116 | glyA | Daci_0116 | Daci_3707 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: ajs:Ajs_0080 threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.905 |
Daci_0116 | trpA | Daci_0116 | Daci_5244 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: ajs:Ajs_0080 threonine dehydratase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.919 |
Daci_0116 | trpB | Daci_0116 | Daci_3688 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: ajs:Ajs_0080 threonine dehydratase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.924 |
Daci_0116 | trpB-2 | Daci_0116 | Daci_5243 | TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; KEGG: ajs:Ajs_0080 threonine dehydratase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.924 |
Daci_0768 | Daci_2369 | Daci_0768 | Daci_2369 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pna:Pnap_3652 glutamine amidotransferase of anthranilate synthase. | PFAM: glycosyl transferase family 3; KEGG: ajs:Ajs_2842 glycosyl transferase, family 3. | 0.906 |
Daci_0768 | trpA | Daci_0768 | Daci_5244 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pna:Pnap_3652 glutamine amidotransferase of anthranilate synthase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.983 |
Daci_0768 | trpB | Daci_0768 | Daci_3688 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pna:Pnap_3652 glutamine amidotransferase of anthranilate synthase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.961 |
Daci_0768 | trpB-2 | Daci_0768 | Daci_5243 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pna:Pnap_3652 glutamine amidotransferase of anthranilate synthase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.964 |
Daci_0768 | trpC | Daci_0768 | Daci_0770 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pna:Pnap_3652 glutamine amidotransferase of anthranilate synthase. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: ajs:Ajs_0370 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. | 0.999 |
Daci_0768 | trpD | Daci_0768 | Daci_0769 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pna:Pnap_3652 glutamine amidotransferase of anthranilate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
Daci_0768 | trpE | Daci_0768 | Daci_0752 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pna:Pnap_3652 glutamine amidotransferase of anthranilate synthase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
Daci_0768 | trpF | Daci_0768 | Daci_5242 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pna:Pnap_3652 glutamine amidotransferase of anthranilate synthase. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: aav:Aave_1216 phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.979 |
Daci_2369 | Daci_0768 | Daci_2369 | Daci_0768 | PFAM: glycosyl transferase family 3; KEGG: ajs:Ajs_2842 glycosyl transferase, family 3. | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: pna:Pnap_3652 glutamine amidotransferase of anthranilate synthase. | 0.906 |
Daci_2369 | trpA | Daci_2369 | Daci_5244 | PFAM: glycosyl transferase family 3; KEGG: ajs:Ajs_2842 glycosyl transferase, family 3. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.923 |
Daci_2369 | trpB | Daci_2369 | Daci_3688 | PFAM: glycosyl transferase family 3; KEGG: ajs:Ajs_2842 glycosyl transferase, family 3. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.813 |
Daci_2369 | trpB-2 | Daci_2369 | Daci_5243 | PFAM: glycosyl transferase family 3; KEGG: ajs:Ajs_2842 glycosyl transferase, family 3. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.826 |
Daci_2369 | trpC | Daci_2369 | Daci_0770 | PFAM: glycosyl transferase family 3; KEGG: ajs:Ajs_2842 glycosyl transferase, family 3. | PFAM: Indole-3-glycerol phosphate synthase; KEGG: ajs:Ajs_0370 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. | 0.922 |
Daci_2369 | trpD | Daci_2369 | Daci_0769 | PFAM: glycosyl transferase family 3; KEGG: ajs:Ajs_2842 glycosyl transferase, family 3. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.408 |
Daci_2369 | trpE | Daci_2369 | Daci_0752 | PFAM: glycosyl transferase family 3; KEGG: ajs:Ajs_2842 glycosyl transferase, family 3. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.977 |
Daci_2369 | trpF | Daci_2369 | Daci_5242 | PFAM: glycosyl transferase family 3; KEGG: ajs:Ajs_2842 glycosyl transferase, family 3. | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: aav:Aave_1216 phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.917 |