STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_0010PFAM: protein of unknown function DUF305 KEGG: psa:PST_3374 hypothetical protein, conserved in bacteria. (173 aa)    
Predicted Functional Partners:
Dshi_1259
Heavy metal translocating P-type ATPase.
 
  
 0.567
elaA
PFAM: GCN5-related N-acetyltransferase KEGG: rsh:Rsph17029_2788 GCN5-related N-acetyltransferase.
       0.533
Dshi_0011
KEGG: rsq:Rsph17025_0047 hypothetical protein, bad swissprot hit to Multiple PDZ domain protein from rattus norvegicus involved in cell junction/cell projection; Immunoglobulin V-Type, subgroup domain (Eukaryota) from T cell surface glycoproteins, junction adhesion molecules, cell surface presentation?.
       0.531
dapE1
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily.
       0.531
Dshi_0014
KEGG: sil:SPO3331 hypothetical protein, Uncharacterized protein conserved in bacteria COG3222, bad swissprot hit to Carboxylesterase bioH (Biotin synthesis protein bioH) from Escherichia coli, Also displays a weak thioesterase activity. Can form a complex with CoA, and may be involved in the condensation of CoA and pimelic acid into pimeloyl-CoA.
       0.531
Dshi_1877
Conserved hypothetical protein; COG: COG4325 - Predicted membrane protein.
 
    0.470
csp2
PFAM: Cold-shock protein DNA-binding SMART: Cold shock protein KEGG: rde:RD1_1402 cold shock protein CspA-related protein, putative.
       0.464
Dshi_0124
TIGRFAM: intracellular protease, PfpI family PFAM: ThiJ/PfpI domain protein KEGG: jan:Jann_1867 peptidase C56, PfpI; PfpI family.
  
     0.456
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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