STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Dshi_0038PFAM: response regulator receiver; transcriptional regulator domain protein KEGG: jan:Jann_0417 two component transcriptional regulator, winged helix family, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, best swissprot hit to Transcriptional regulatory protein yycF from Bacillus subtilis; winged helix family. (228 aa)    
Predicted Functional Partners:
Dshi_3346
KEGG: sil:SPO0094 sensory box sensor histidine kinase/response regulator TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 0.921
Dshi_1893
LOV-regulator, Blue-light sensing; Similar to to known LOV domains (e.g SB1 and SB2 from Pseudomonas putida); highly conserved LOV consensus region including the photoactive Cys. TIGRFAM: TIGR00229 PAS domain S-box; COG: COG0642 - Signal transduction histidine kinase; SMART: SM00091: PAS domain; SM00086: PAC motif, SM00388: Histidine kinase-like ATPases, SM00448 : cheY-homologous receiver domain; PROSITE: PS50112: PAS repeat profile, PS50113: PAC domain profile, PS50110: Response regulatory domain profile, PS50109: Histidine kinase domain profile; PFAM: PF00072: Response regulator rece [...]
 
 
 0.910
Dshi_0334
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; low swissprot hit to Sensor protein zraS (a membrane-associated protein kinase that phosphorylates zraR in response to high concentrations of zinc or lead in the medium) from Salmonella typhimurium and high Ref ZP hit to periplasmic sensor signal transduction histidine kinase from R.
 
 
 0.852
Dshi_0824
Histidine kinase; C-Terminal domain of arcB (aerobic respiration control), no PAS domain (sensor).
 
 
 0.851
phoR
Histidine kinase; SWISSPROT P08400: Phosphate regulon sensor protein phoR; PFAM: PF02518, PF00512; SMART: SM00387, SM00091; SM00388; COG: COG5002-Signal transduction histidine kinase; putative phosphate regulon sensor protein (phoR).
 
 0.784
fdhB
High similarity to Respiratory-chain NADH dehydrogenase domain 24 kDa and 51 kDa subunits(PMID:2187144).
   
 
 0.766
Dshi_2708
Sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein.
 
 0.737
Dshi_0211
Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein KEGG: rsh:Rsph17029_0315 histidine kinase.
 
 0.723
Dshi_2498
Integral membrane sensor signal transduction histidine kinase; Swiss-Prot: P0AEJ4-Osmolarity sensor protein (envZ) PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein KEGG: sil:SPOA0358 sensor histidine kinase; colocated with response regulator.
 
 0.713
Dshi_1921
Histidine kinase; COG: COG0642 - Signal transduction histidine kinase; PFAM: PF02518, PF00672, PF00512.
 
 0.637
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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