STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_0514Bad swissprot to Transcriptional regulatory protein fixJ from Azorhizobium caulinodans; low Ref ZP hit to putative two-component response regulator [Roseovarius sp. HTCC2601]; PFAM00072 response regulator receiver; COG4566, TtrR, Response regulator. (60 aa)    
Predicted Functional Partners:
Dshi_0515
Histidine kinase; Unsure GC frame plot; - PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; NCBI conserved domains: HisKA; middle swissprot hit to Sensor protein fixL; good Ref ZP hit to probable sensor histidine kinase of two-component system from Roseovarius sp. HTCC2601.
  
 
 0.817
Dshi_0516
Putative two-component sensor kinase; Pfam04392, ABC_sub_bind, ABC transporter substrate binding protein; no significant swissprot; good Ref ZP hit to probable sensor histidine kinase of two-component system from Roseovarius sp. HTCC2601; unsure GC frame plot.
       0.783
Dshi_0513
Pfam00196, GerE, Bacterial regulatory proteins, luxR family; low swissprot hit to Transcriptional regulatory protein fixJ from Sinorhizobium meliloti; middle Ref ZP hit to putative two-component response regulator [Roseovarius sp. HTCC2601], unsure GC frame plot; LuxR family.
  
    0.775
Dshi_1893
LOV-regulator, Blue-light sensing; Similar to to known LOV domains (e.g SB1 and SB2 from Pseudomonas putida); highly conserved LOV consensus region including the photoactive Cys. TIGRFAM: TIGR00229 PAS domain S-box; COG: COG0642 - Signal transduction histidine kinase; SMART: SM00091: PAS domain; SM00086: PAC motif, SM00388: Histidine kinase-like ATPases, SM00448 : cheY-homologous receiver domain; PROSITE: PS50112: PAS repeat profile, PS50113: PAC domain profile, PS50110: Response regulatory domain profile, PS50109: Histidine kinase domain profile; PFAM: PF00072: Response regulator rece [...]
   
 
 0.632
Dshi_3346
KEGG: sil:SPO0094 sensory box sensor histidine kinase/response regulator TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein; PAC repeat-containing protein.
   
 
 0.632
Dshi_2567
Multi-sensor signal transduction histidine kinase; Swiss-Prot: P26489-Sensor protein fixL TIGRFAM: PAS sensor protein PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Cache domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein SMART: PAS domain containing protein, colocated with response regulator.
  
 
 0.477
araF2
PFAM: periplasmic binding protein/LacI transcriptional regulator; COG4213, XylF, ABC-type xylose transport system, periplasmic component; low swissprot hit to D-ribose-binding protein precursor from Bacillus subtilis; High Ref YP Hit to sugar ABC transporter, substrate-binding protein, putative from Roseobacter denitrificans OCh 114; periplasmic component.
       0.415
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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