STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_0537PFAM: carbohydrate kinase FGGY; NCBI conserved domains: AraB, XylB; good swissprot hit to Ribulokinase from Bacillus clausii KSM-K16; high Ref YP hit to carbohydrate kinase FGGY [Sinorhizobium medicae WSM419]. (497 aa)    
Predicted Functional Partners:
rpe
PFAM: ribulose-phosphate 3-epimerase KEGG: rsp:RSP_2864 pentose-5-phosphate-3-epimerase.
    
 0.707
pdhC2
Dihydrolipoamide acetyltransferase; PFAM: alpha/beta hydrolase fold; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; middle swissprot hit to Acetoin dehydrogenase E2 component from Pseudomonas putida; high Ref YP hit to branched-chain alpha-keto acid dehydrogenase subunit E2 from Sinorhizobium medicae WSM419; unsure GC frame plot; pyruvate dehydrogenase E2 component.
       0.675
deoR2
Transcriptional regulator; PFAM: putative sugar-binding domain protein; NCBI conserved domains: pfam04198, Sugar-bind and COG2390, DeoR; middle swissprot hit to Deoxyribonucleoside regulator from Bacillus subtilis; good Ref YP hit to transcriptional regulator, DeoR family [Sinorhizobium medicae WSM419]; DeoR family.
 
    0.669
pdhB1
Pyruvate dehydrogenase E1 component subunit beta; PFAM: Transketolase central region; Transketolase domain protein; high swissprot hit to Pyruvate dehydrogenase E1 component subunit beta from Rickettsia bellii RML369-C; high Ref YP hit to Transketolase central region [Sinorhizobium medicae WSM419]; Transketolase central region.
  
    0.612
pdhA2
PFAM: dehydrogenase E1 component; good swissprot hit to Pyruvate dehydrogenase E1 component subunit alpha from Zymomonas mobilis; high Ref YP hit to dehydrogenase E1 component [Sinorhizobium medicae WSM419].
  
    0.608
Dshi_0533
PFAM: Xylose isomerase domain protein TIM barrel; NCBI conserved domains: cd00019, AP2Ec, AP endonuclease family 2; middle swissprot hit to Uncharacterized protein sll1304 from Synechocystis sp. PCC 6803; high Ref YP hit to Xylose isomerase domain protein TIM barrel [Sinorhizobium medicae WSM419].
  
  
 0.575
araF1
NCBI conserved domains: COG4213, XylF, ABC-type xylose transport system, periplasmic component; low swissprot hit to Uncharacterized protein yneA precursor from Escherichia coli K12; high Ref ZP hit to putative periplasmic substrate-binding protein, ABC-type sugar transporter [Aurantimonas sp. SI85-9A1]; periplasmic component.
 
    0.545
xylA
Xylose isomerase; PROSITE: PS00172, PS00173; PFAM: PF01261; SWISSPROT Q3IYM4: Xylose isomerase; TIGRFAM: TIGR02630; COG: COG2115; Belongs to the xylose isomerase family.
  
  
 0.504
fucA
PFAM: class II aldolase/adducin family protein; COG0235, AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; good swissprot hit to L-fuculose phosphate aldolase from Escherichia coli K12; good Ref ZP hit to L-fuculose phosphate aldolase [Stappia aggregata IAM 12614]; unsure GC frame plot.
 
  
 0.479
glpD
Glycerol-3-phosphate dehydrogenase; PFAM: FAD dependent oxidoreductase; NCBI conserved domains: PRK12266, glpD, glycerol-3-phosphate dehydrogenase; high swissprot hit to Glycerol-3-phosphate dehydrogenase from Pseudomonas aeruginosa; high Ref ZP hit to aerobic glycerol-3-phosphate dehydrogenase [Roseovarius sp. HTCC2601; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
  
   
 0.465
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.