STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mreBTIGRFAM: cell shape determining protein, MreB/Mrl family PFAM: cell shape determining protein MreB/Mrl; high swissprot hit to Rod shape-determining protein mreB from Escherichia coli K12; high Ref ZP hit to rod shape-determining protein MreB [Rhodobacterales bacterium HTCC2150]. (345 aa)    
Predicted Functional Partners:
mreC
TIGRFAM: rod shape-determining protein MreC PFAM: Rod shape-determining protein MreC; NCBI conserved domains: PRK10900, cell wall structural complex MreBCD transmembrane component MreC; low swissprot hit to Rod shape-determining protein mreC from Haemophilus influenzae; high Ref ZP hit to rod shape-determining protein MreC [Roseovarius nubinhibens ISM].
 
 
 0.995
mreD1
Rod shape-determining protein MreD; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 
 0.987
ftsI1
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain, NCBI conserved domains: COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2; high swissprot hit to Penicillin-binding protein 2 from Haemophilus influenzae; high Ref ZP hit to penicillin-binding protein 2 [Roseobacter sp. CCS2]; penicillin-binding protein (pbp-2).
 
 0.979
Dshi_1183
Conserved hypothetical protein; Conserved in Rhodobacteraceae.
 
 
 0.860
ftsZ
Cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.850
mreD2
Putative rod shape-determining protein MreD; No significant swissprot; no conserved domains, except from one signalpep. and four transmembr. regions; low Ref ZP hit to putative rod shape-determining protein MreD [Roseobacter sp. CCS2].
  
    0.782
Dshi_0590
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; middle swissprot hit to Putative 2-hydroxyacid dehydrogenase ycdW from Escherichia coli K12; high Ref ZP hit to D-isomer specific 2-hydroxyacid dehydrogenase family protein from Roseovarius sp. 217.
       0.781
Dshi_2424
Swiss-Prot: P0ABG4-Cell division protein ftsW TIGRFAM: cell division protein FtsW PFAM: cell cycle protein; colocated with ftsA,ftsZ and (putative)ftsQ; Belongs to the SEDS family.
 
 
 0.715
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
    0.683
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
  
 0.679
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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