STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_0670Ibu; PFAM: Haloacid dehalogenase domain protein hydrolase; NCBI conserved domains: COG1011, Predicted hydrolase (HAD superfamily); bad swissprot hit to Uncharacterized HAD-hydrolase MTH_209 from Methanothermobacter thermautotrophicus str. Delta H; high Ref YP hit to Haloacid dehalogenase domain protein hydrolase [Rhodobacter sphaeroides ATCC 17025]. (234 aa)    
Predicted Functional Partners:
dacC2
PFAM: beta-lactamase; peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; NCBI conserved domains: dacC; middle swissprot hit to D-alanyl-D-alanine carboxypeptidase dacC precursor from Escherichia coli K12; high Ref YP hit to D-alanyl-D-alanine carboxypeptidase family protein [Roseobacter denitrificans OCh 114].
       0.652
ribD
Riboflavin biosynthesis protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.501
rsmC
PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; NCBI conserved domains: rsmC; low swissprot hit to Ribosomal RNA small subunit methyltransferase C from Escherichia coli K12; high Ref ZP hit to Possible ribosomal RNA small subunit methyltransferase C RsmC from Roseobacter sp. CCS2; Belongs to the methyltransferase superfamily.
 
    0.500
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.402
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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