close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_1069Fe-S metabolism associated SufE; This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export. (164 aa)    
Predicted Functional Partners:
sufS
Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
 0.993
sufB
sufB; SWISSPROT P77522: Protein sufB; TIGRFAM: TIGR01980 FeS assembly protein SufB; COG: COG0719 - ABC-type transport system involved in Fe-S cluster assembly, permease component; SUPERFAMILY: SSF101960.
 
 
 0.858
sufD
sufD; SWISSPROT P77689: Protein sufD; COG: COG0719 - ABC-type transport system involved in Fe-S cluster assembly, permease component; PFAM: pfam01458; SUPERFAMILY SSF101960: Stabilizer of iron transporter SufD.
 
 
 0.848
sufC
SWISSPROT P77499: Probable ATP-dependent transporter sufC; TIGRFAM: TIGR01978 FeS assembly ATPase SufC; PANTHER: PTHR19222:SF6-ABC TRANSPORTER; PFAM: PF00005; PROSITE: PS00211, PS50893; SMART: SM00382.
 
 
 0.844
Dshi_1280
Aminotransferase class V; Domain is found in amino transferases, and other enzymes including cysteine desulphurase, PLP dependent enzyme.
  
 
 0.826
Dshi_1068
Hypothetical protein; Conserved in Rhodobacteraceae.
  
    0.725
Dshi_1660
Transcriptional regulator; TIGRFAM: TIGR00738; PFAM: PF02082; SUPERFAMILY: SSF46785.
     
 0.531
hmuT
PFAM: periplasmic binding protein; good swissprot hit to Hemin-binding periplasmic protein hmuT precursor from Yersinia pestis; high Ref YP hit to hemin ABC transporter, periplasmic hemin-binding protein [Roseobacter denitrificans OCh 114].
   
  
 0.512
fur
Fur family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes; Fur family.
      
 0.511
Dshi_2348
Conserved hypothetical protein; PFAM: protein of unknown function DUF59.
 
     0.439
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
Server load: medium (42%) [HD]