STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_1258Short-chain dehydrogenase/reductase SDR; Most enzymes of this family are NAD/NADP-dependent oxidoreductases. (247 aa)    
Predicted Functional Partners:
gap3
Swiss-Prot: P09124-Glyceraldehyde-3-phosphate dehydrogenase 1 PFAM: glyceraldehyde 3-phosphate dehydrogenase TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; phosphorylating; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  0.837
gap1
SWISSPROT P00362: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057 - Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: pfam02800 pfam00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  0.835
pdhB2
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 0.835
Dshi_1254
Glyceraldehyde-3-phosphate dehydrogenase; Tetrameric NAD-binding enzyme involved in glycolysis and glyconeogenesis; type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  0.834
gap2
SWISSPROT P00362: Glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: TIGR01534 glyceraldehyde-3-phosphate dehydrogenase, type I; COG: COG0057 - Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; PFAM: pfam02800 pfam00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  0.834
ipgm
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.825
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 0.824
pykA
KEGG: rsp:RSP_1766 pyruvate kinase TIGRFAM: pyruvate kinase PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; high swissprot; Belongs to the pyruvate kinase family.
   
 0.822
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.820
pgm
SWISSPROT P39671: Phosphoglucomutase; COG: COG0033 - Phosphoglucomutase; PFAM: PF02880, PF02879, PF02878, PF00408.
   
 0.819
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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