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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dshi_1604COG: COG1024-Enoyl-CoA hydratase/carnithine racemase; PFAM: pfam00378; SWISSPROT P76082: Probable enoyl-CoA hydratase paaF. (264 aa)    
Predicted Functional Partners:
hbdA
PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding KEGG: sil:SPO0717 3-hydroxybutyryl-CoA dehydrogenase; high swissprot, good RBS site AGGAT.
 
 0.941
Dshi_1893
LOV-regulator, Blue-light sensing; Similar to to known LOV domains (e.g SB1 and SB2 from Pseudomonas putida); highly conserved LOV consensus region including the photoactive Cys. TIGRFAM: TIGR00229 PAS domain S-box; COG: COG0642 - Signal transduction histidine kinase; SMART: SM00091: PAS domain; SM00086: PAC motif, SM00388: Histidine kinase-like ATPases, SM00448 : cheY-homologous receiver domain; PROSITE: PS50112: PAS repeat profile, PS50113: PAC domain profile, PS50110: Response regulatory domain profile, PS50109: Histidine kinase domain profile; PFAM: PF00072: Response regulator rece [...]
   
 
 0.799
Dshi_3346
KEGG: sil:SPO0094 sensory box sensor histidine kinase/response regulator TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein; PAC repeat-containing protein.
   
 
 0.799
Dshi_2676
Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein.
   
 
 0.789
Dshi_2708
Sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein SMART: PAS domain containing protein.
   
 
 0.789
Dshi_3332
Sensor histidine kinase/response regulator; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein KEGG: rde:RD1_0357 hybrid sensory histidine kinase, putative.
   
 
 0.789
Dshi_1963
Putative modular PKS system; SWISSPROT: Q03131: Erythronolide synthase, modules 1 and 2; Q03132: Erythronolide synthase, modules 3 and 4; PFAM: PF03060, PF08659, PF00109, PF02801, PF00698; TIGRFAM: TIGR02813 polyketide-type polyunsaturated fatty acid synthase PfaA; COG: COG3321 - Polyketide synthase modules and related proteins.
  
 0.726
thlA
KEGG: jan:Jann_4050 acetyl-CoA C-acetyltransferase TIGRFAM: acetyl-CoA acetyltransferase PFAM: Thiolase; good swissprot hit to Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase) from Clostridium acetobutylicum; found domain accords to thiolase II; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.696
fadA
Thiolase, Reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.696
atoB
KEGG: sil:SPO0326 acetyl-CoA acetyltransferase TIGRFAM: acetyl-CoA acetyltransferase PFAM: Thiolase; Acetoacetyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.696
Your Current Organism:
Dinoroseobacter shibae
NCBI taxonomy Id: 398580
Other names: D. shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DFL 12, Dinoroseobacter shibae DFL 12 = DSM 16493, Dinoroseobacter shibae DSM 16493, Dinoroseobacter shibae DSM 16493 = DFL 12, Jannaschia sp. DFL-12
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