node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purC | purD | Dshi_1076 | Dshi_2728 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | 0.942 |
purC | purE | Dshi_1076 | Dshi_0681 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.997 |
purC | purF | Dshi_1076 | Dshi_2132 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.962 |
purC | purH | Dshi_1076 | Dshi_0358 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | KEGG: rde:RD1_0655 bifunctional purine biosynthesis protein PurH TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; high swissprot to Bifunctional purine biosynthesis protein purH from Brucella suis. | 0.956 |
purC | purK | Dshi_1076 | Dshi_0680 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.981 |
purC | purL | Dshi_1076 | Dshi_1713 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.920 |
purC | purM | Dshi_1076 | Dshi_1889 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine cyclo ligase; TIGRFAM: TIGR00878 phosphoribosylaminoimidazole synthetase; COG: COG0150 - Phosphoribosylaminoimidazole (AIR) synthetase. | 0.957 |
purC | purN | Dshi_1076 | Dshi_1888 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.942 |
purC | purQ | Dshi_1076 | Dshi_1079 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.973 |
purC | purS | Dshi_1076 | Dshi_1077 | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.963 |
purD | purC | Dshi_2728 | Dshi_1076 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylaminoimidazole- succinocarboxamidesynthase; Purine nucleotid biosynthesis, Reaction: ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate; Belongs to the SAICAR synthetase family. | 0.942 |
purD | purE | Dshi_2728 | Dshi_0681 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.997 |
purD | purF | Dshi_2728 | Dshi_2132 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.999 |
purD | purH | Dshi_2728 | Dshi_0358 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | KEGG: rde:RD1_0655 bifunctional purine biosynthesis protein PurH TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; high swissprot to Bifunctional purine biosynthesis protein purH from Brucella suis. | 0.976 |
purD | purK | Dshi_2728 | Dshi_0680 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.952 |
purD | purL | Dshi_2728 | Dshi_1713 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.937 |
purD | purM | Dshi_2728 | Dshi_1889 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine cyclo ligase; TIGRFAM: TIGR00878 phosphoribosylaminoimidazole synthetase; COG: COG0150 - Phosphoribosylaminoimidazole (AIR) synthetase. | 0.997 |
purD | purN | Dshi_2728 | Dshi_1888 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | Dshi_2728 | Dshi_1079 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.994 |
purD | purS | Dshi_2728 | Dshi_1077 | Swiss-Prot: P15640- Phosphoribosylamine--glycine ligase TIGRFAM: phosphoribosylamine--glycine ligase PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] | 0.917 |